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Published 10:52 17 Sept 2021 BST
Updated 13:26 17 Sept 2021 BST
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"He had this hold on the set. The network and studio came down and we had sessions with them. I think he was just done with the show."
Adding that Patrick "didn’t like the inconvenience of coming in every day" as his stint on the series came to an end, it was also claimed that his co-star Ellen Pompeo also began to feel the tension.
James added: 'He didn’t like the inconvenience of coming in every day and working. He and Shonda [Rhimes] were at each other’s throats."
Fellow producer Jeannie Renshaw also said: "A lot of the complaining … I think Shonda finally witnessed it herself, and that was the final straw.
"Shonda had to say to the network, ‘If he doesn’t go, I go.’ Nobody wanted him to leave, because he was the show. He and Ellen. Patrick is a sweetheart. It messes you up, this business."
According to the book, Patrick began "complaining" if he had to stay "late" for longer shoots, which began getting on Ellen's nerves towards the end of season 11.
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